Program

42
1
1

Journal Year Published

14
5
16
4
1
1
1
1

Author

43
182
174
134
134
125
118
116
114
108
88
86
81
73
56
51
50
43
42
34

Category

25
23
20
4
2
1
1

Keyword

9
8
6
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1

Journal

5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.


Kearney SE, et al.


ACS Cent Sci , (4), 1727-1741, 2018.

Article Pubmed

Sample image from publication page

Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.


Iniguez AB, Alexe G, Wang EJ, Roti G, Patel S, Chen L, Kitara S, Conway A, Robichaud AL, Stolte B, Bandopadhayay P, Goodale A, Pantel S, Lee Y, Cheff D, Hall M, Guha R, Davis MI, Menard M, Nasholm N, Weiss WA, Qi J, Beroukhim R, Piccioni F, Johannessen C, Stegmaier K


Cancer Cell , (34), 922-938.e7, 2018.

Article Pubmed

Sample image from publication page

KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations.


Liu X, Zhang SM, McGeary MK, Krykbaeva I, Lai L, Jansen DJ, Kales S, Simeonov A, Hall M, Kelly DP, Bosenberg MW, Yan Q


Mol. Cancer Ther. , 2018.

Article Pubmed

Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.


Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai Bantukallu G, Mott BT, Jansen DJ, Kales S, Henderson M, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page

Glypican-3 Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.


Fu Y, Urban D, Nani RR, Zhang YF, Li N, Fu H, Shah H, Gorka AP, Guha R, Chen L, Hall M, Schnermann MJ, Ho M


Hepatology , 2018.

Article Pubmed

Discovery and lead identification of quinazoline-based BRD4 inhibitors.


Yang SM, Urban D, Yoshioka M, Strovel JW, Fletcher S, Wang A, Xu X, Shah P, Hu X, Hall M, Jadhav A, Maloney DJ


Bioorg. Med. Chem. Lett. , (28), 3483-3488, 2018.

Article Pubmed

Sample image from publication page

KDM5 histone demethylases repress immune response via suppression of STING.


Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai Bantukallu G, Kales S, Henderson M, Hu X, Jadhav A, Maloney DJ, Simeonov A, Zhu S, Iwasaki A, Hall M, Cheng X, Shadel GS, Yan Q


PLoS Biol. , (16), e2006134, 2018.

Article Pubmed

Sample image from publication page

The Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.




Clin Transl Sci , 2018.

Article Pubmed

Sample image from publication page