Program

769
545
101
89
87
35
26
15
15
11
10
10
9
4
2

Journal Year Published

52
96
174
325
327
378
120
64
48
48
35
17
9
4
4
3
2
2
2
2

Author

170
168
126
121
117
114
107
106
106
79
77
73
64
53
50
43
41
38
36
32

Category

329
319
289
96
85
67
21
18
15
14
3
2

Keyword

1205
587
534
377
332
295
206
191
158
143
121
116
108
106
96
94
90
82
80
80

Journal

48
47
43
28
25
21
20
17
16
15
15
14
14
14
13
13
13
13
12
12

NCATS Publications

miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential.


Meyer SE, Muench DE, Rogers AM, Newkold TJ, Orr E, O'Brien E, Perentesis JP, Doench JG, Lal A, Morris P, Thomas C, Lieberman J, McGlinn E, Aronow BJ, Salomonis N, Grimes HL


J. Exp. Med. , (215), 2115-2136, 2018.

Article Pubmed

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MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.


Yohe ME, Gryder BE, Shern JF, Song YK, Chou HC, Sindiri S, Mendoza A, Patidar R, Zhang X, Guha R, Butcher D, Isanogle KA, Robinson CM, Luo X, Chen JQ, Walton A, Awasthi P, Edmondson EF, Difilippantonio S, Wei JS, Zhao K, Ferrer-Alegre M, Thomas C, Khan J


Sci Transl Med , (10), 2018.

Article Pubmed

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Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.


Zanos P, Moaddel R, Morris P, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas C, Zarate CA, Gould TD


Pharmacol. Rev. , (70), 621-660, 2018.

Article Pubmed

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Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.


Dyall J, Nelson EA, DeWald LE, Guha R, Hart BJ, Zhou H, Postnikova E, Logue J, Vargas WM, Gross R, Michelotti J, Deiuliis N, Bennett RS, Crozier I, Holbrook MR, Morris P, Klumpp-Thomas C, McKnight C, Mierzwa T, Shinn P, Glass PJ, Johansen LM, Jahrling PB, Hensley LE, Olinger GG, Thomas C, White JM


J. Infect. Dis. , 2018.

Article Pubmed

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Genome editing to 're-write' wrongs.


Perry ME, Valdes K, Wilder E, Austin C, Brooks P


Nat Rev Drug Discov , 2018.

Article Pubmed

A multiprotein supercomplex controlling oncogenic signalling in lymphoma.


Phelan JD, et al.


Nature , 2018.

Article Pubmed

Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells.


Ferrer-Alegre M, Gosline SJC, Stathis M, Zhang X, Guo X, Guha R, Ryman DA, Wallace MR, Kasch-Semenza L, Hao H, Ingersoll R, Mohr D, Thomas C, Verma S, Guinney J, Blakeley JO


Sci Data , (5), 180106, 2018.

Article Pubmed

The Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.




Clin Transl Sci , 2018.

Article Pubmed

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