Program

99
92
5
3
2
1
1

Journal Year Published

3
12
16
11
20
10
8
9
10
12
12
10
12
4

Author

149
201
181
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
43
32
19
18
16
15
15
14
13
13
12
12
12
11
11
10
10
10
9

Journal

16
13
12
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2

NCATS Publications

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.


Palsson-McDermott EM, Curtis AM, Goel G, Lauterbach MA, Sheedy FJ, Gleeson LE, van den Bosch MW, Quinn SR, Domingo-Fernandez R, Johnston DG, Jiang J, Jiang J, Israelsen WJ, Keane J, Thomas C, Clish C, Vander Heiden M, Vanden Heiden M, Xavier RJ, O'Neill LA


Cell Metab. , (21), 65-80, 2015.

Article Pubmed

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Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity.


Lu G, Lomonosova E, Cheng X, Moran EA, Meyers MJ, Le Grice SF, Thomas C, Jiang J, Meck C, Hirsch DR, D'Erasmo MP, Suyabatmaz DM, Murelli RP, Tavis JE


Antimicrob. Agents Chemother. , (59), 1070-9, 2015.

Article Pubmed

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RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.


Li J, Vootukuri S, Shang Y, Negri A, Jiang J, Nedelman M, Diacovo TG, Filizola M, Thomas C, Coller BS


Arterioscler. Thromb. Vasc. Biol. , (34), 2321-9, 2014.

Article Pubmed

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Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.


Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer-Alegre M, Joshi S, Nerle S, Sandy P, Normant E, Thomas C, Staudt LM


Proc. Natl. Acad. Sci. U.S.A. , (111), 11365-70, 2014.

Article Pubmed

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Tofacitinib suppresses antibody responses to protein therapeutics in murine hosts.


Onda M, Ghoreschi K, Steward-Tharp S, Thomas C, O'Shea JJ, Pastan IH, FitzGerald DJ


J. Immunol. , (193), 48-55, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.


Jiang J, McCoy JG, Shen M, LeClair C, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G, Choi WS, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas C


Bioorg. Med. Chem. Lett. , (24), 1148-53, 2014.

Article Pubmed

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