Program

84
22
4
3
1
1

Journal Year Published

3
17
12
19
13
8
7
8
2
1

Author

90
183
175
135
134
127
119
118
115
108
87
81
74
57
52
50
44
43
42
34

Category

57
31
27
7
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.


Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer-Alegre M, Titus S, Zheng W, Sibley DR, Marugan J


J. Med. Chem. , (57), 3450-63, 2014.

Article Pubmed

Sample image from publication page

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

Sample image from publication page

A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis.


Samie M, Wang X, Zhang X, Goschka A, Li X, Cheng X, Gregg E, Azar M, Zhuo Y, Garrity AG, Gao Q, Slaugenhaupt S, Pickel J, Zolov SN, Weisman LS, Lenk GM, Titus S, Bryant-Genevier M, Southall N, Juan M, Ferrer-Alegre M, Xu H


Dev. Cell , (26), 511-24, 2013.

Article Pubmed

Sample image from publication page

Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.


Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer-Alegre M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, Cuzzola M, Maciejewski JP, Mulloy JC, Starczynowski DT


Cancer Cell , (24), 90-104, 2013.

Article Pubmed

Sample image from publication page

Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins.


Casson L, Howell L, Mathews LA, Ferrer-Alegre M, Southall N, Guha R, Keller JM, Thomas C, Siskind LJ, Beverly LJ


PLoS ONE , (8), e54525, 2013.

Article Pubmed

Sample image from publication page

A high-throughput screening assay using Krabbe disease patient cells.


Ribbens J, Whiteley G, Furuya H, Southall N, Hu X, Marugan J, Ferrer-Alegre M, Maegawa GH


Anal. Biochem. , (434), 15-25, 2013.

Article Pubmed

Sample image from publication page

A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.


Mathews LA, Keller JM, Goodwin BL, Guha R, Shinn P, Mull R, Thomas C, de Kluyver RL, Sayers TJ, Ferrer-Alegre M


J Biomol Screen , (17), 1231-42, 2012.

Article Pubmed

Sample image from publication page

Discovery of a novel noniminosugar acid α glucosidase chaperone series.


Xiao J, Westbroek W, Motabar O, Lea WA, Hu X, Velayati A, Zheng W, Southall N, Gustafson AM, Goldin E, Sidransky E, Liu K, Simeonov A, Tamargo RJ, Ribes A, Matalonga L, Ferrer-Alegre M, Marugan J


J. Med. Chem. , (55), 7546-59, 2012.

Article Pubmed

Sample image from publication page