Program

116
16
6
4
3

Journal Year Published

9
10
12
5
13
10
12
12
12
7
5
15
10
1

Author

133
201
181
149
139
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

56
45
28
20
13
6
5
4
3
1

Keyword

63
35
27
25
22
17
17
17
14
11
10
10
9
9
9
9
8
7
7
7

Journal

13
9
8
7
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2

NCATS Publications

Macrophage models of Gaucher disease for evaluating disease pathogenesis and candidate drugs.


Aflaki E, Stubblefield BK, Maniwang E, Lopez G, Moaven N, Goldin E, Marugan J, Patnaik S, Dutra A, Southall N, Zheng W, Tayebi N, Sidransky E


Sci Transl Med , (6), 240ra73, 2014.

Article Pubmed

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Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.


Hoskins JW, Ofori LO, Chen C, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan J, Zheng W, Austin C, Disney MD, Miller BL, Thornton CA


Nucleic Acids Res. , (42), 6591-602, 2014.

Article Pubmed

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Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.


Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer-Alegre M, Javitch JA, Beuming T, Shi L, Southall N, Marugan J, Sibley DR


Mol. Pharmacol. , (86), 96-105, 2014.

Article Pubmed

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Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.


Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer-Alegre M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R


J. Biol. Chem. , (289), 16349-61, 2014.

Article Pubmed

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Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.


Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer-Alegre M, Titus S, Zheng W, Sibley DR, Marugan J


J. Med. Chem. , (57), 3450-63, 2014.

Article Pubmed

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An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines.


de Souza A, Bittker JA, Lahr DL, Brudz S, Chatwin S, Oprea TI, Waller A, Yang JJ, Southall N, Guha R, Schürer SC, Vempati UD, Southern MR, Dawson ES, Clemons PA, Chung TD


J Biomol Screen , (19), 614-27, 2014.

Article Pubmed

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Chemical signatures and new drug targets for gametocytocidal drug development.


Sun W, Tanaka TQ, Magle CT, Huang W, Southall N, Huang R, Dehdashti SJ, McKew JC, Williamson KC, Zheng W


Sci Rep , (4), 3743, 2014.

Article Pubmed

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