Program

127
5
3
2
1

Journal Year Published

3
15
11
11
8
18
12
8
5
11
8
13
2
2

Author

127
183
175
135
134
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

59
49
44
23
15
4
4
1
1
1

Keyword

63
33
27
26
22
21
21
20
14
13
12
10
10
10
9
8
8
8
7
7

Journal

23
15
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1

NCATS Publications

A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.


Liang Q, Dexheimer TS, Zhang P, Rosenthal AS, Villamil MA, You C, Zhang Q, Chen J, Ott CA, Sun H, Luci D, Yuan B, Simeonov A, Jadhav A, Xiao H, Wang Y, Maloney DJ, Zhuang Z


Nat. Chem. Biol. , (10), 298-304, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.


Luci D, Jameson JB, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, Jadhav A, Simeonov A, Holman TR, Maloney DJ


J. Med. Chem. , (57), 495-506, 2014.

Article Pubmed

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A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding.


McCallum MM, Pawlak AJ, Shadrick WR, Simeonov A, Jadhav A, Yasgar A, Maloney DJ, Arnold LA


Anal Bioanal Chem , (406), 1867-75, 2014.

Article Pubmed

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Inhibition of DNA glycosylases via small molecule purine analogs.


Jacobs AC, Calkins MJ, Jadhav A, Dorjsuren D, Maloney D, Simeonov A, Jaruga P, Dizdaroglu M, McCullough AK, Lloyd RS


PLoS ONE , (8), e81667, 2013.

Article Pubmed

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Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase.


Rosenthal AS, Dexheimer TS, Gileadi O, Nguyen GH, Chu WK, Hickson ID, Jadhav A, Simeonov A, Maloney DJ


Bioorg. Med. Chem. Lett. , (23), 5660-6, 2013.

Article Pubmed

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Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion.


Srinivasan P, Yasgar A, Luci D, Beatty WL, Hu X, Andersen J, Narum DL, Moch JK, Sun H, Haynes JD, Maloney DJ, Jadhav A, Simeonov A, Miller LH


Nat Commun , (4), 2261, 2013.

Article Pubmed

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Are hERG channel blockers also phospholipidosis inducers?


Sun H, Xia M, Shahane SA, Jadhav A, Austin C, Huang R


Bioorg. Med. Chem. Lett. , (23), 4587-90, 2013.

Article Pubmed

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