Program

127
5
3
2
1

Journal Year Published

3
15
11
11
8
18
12
8
5
11
8
13
2
2

Author

127
183
175
135
134
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

59
49
44
23
15
4
4
1
1
1

Keyword

63
33
27
26
22
21
21
20
14
13
12
10
10
10
9
8
8
8
7
7

Journal

23
15
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1

NCATS Publications

A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2.


Jameson JB, Kantz A, Schultz L, Kalyanaraman C, Jacobson MP, Maloney DJ, Jadhav A, Simeonov A, Holman TR


PLoS ONE , (9), e104094, 2014.

Article Pubmed

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Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.


Yeung J, Tourdot BE, Fernandez-Perez P, Vesci J, Ren J, Smyrniotis CJ, Luci D, Jadhav A, Simeonov A, Maloney DJ, Holman TR, McKenzie SE, Holinstat M


Blood , (124), 2271-9, 2014.

Article Pubmed

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A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein.


Carver J, Dexheimer TS, Hsu D, Weng MT, Smith JL, Guha R, Jadhav A, Simeonov A, Luo J


PLoS ONE , (9), e103836, 2014.

Article Pubmed

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Biochemical assays for the discovery of TDP1 inhibitors.


Marchand C, Huang SY, Dexheimer TS, Lea WA, Mott BT, Chergui A, Naumova A, Stephen AG, Rosenthal AS, Rai Bantukallu G, Murai J, Gao R, Maloney DJ, Jadhav A, Jorgensen WL, Simeonov A, Pommier Y


Mol. Cancer Ther. , (13), 2116-26, 2014.

Article Pubmed

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Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.


Abdel-Fatah TM, Russell R, Albarakati N, Maloney DJ, Dorjsuren D, Rueda OM, Moseley P, Mohan V, Sun H, Abbotts R, Mukherjee A, Agarwal D, Illuzzi JL, Jadhav A, Simeonov A, Ball G, Chan S, Caldas C, Ellis IO, Wilson DM, Madhusudan S


Mol Oncol , (8), 1326-38, 2014.

Article Pubmed

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Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy.


Abbotts R, Jewell R, Nsengimana J, Maloney DJ, Simeonov A, Seedhouse C, Elliott F, Laye J, Walker C, Jadhav A, Grabowska A, Ball G, Patel PM, Newton-Bishop J, Wilson DM, Madhusudan S


Oncotarget , (5), 3273-86, 2014.

Article Pubmed

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Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform.


Murai J, Marchand C, Shahane SA, Sun H, Huang R, Zhang Y, Chergui A, Ji J, Doroshow JH, Jadhav A, Takeda S, Xia M, Pommier Y


DNA Repair (Amst.) , (21), 177-82, 2014.

Article Pubmed

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Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.


Rai Bantukallu G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, Holman TR


J. Med. Chem. , (57), 4035-48, 2014.

Article Pubmed

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