Program

769
513
90
82
82
33
26
15
13
11
10
10
9
4
2

Journal Year Published

2
82
161
316
323
373
114
57
46
43
32
16
7
3
2
1
1
2
1
1

Author

163
155
118
114
109
109
103
102
98
74
70
69
62
50
50
38
37
35
31
30

Category

295
289
273
86
82
55
21
18
15
14
2
2

Keyword

1154
568
515
344
325
290
204
177
154
142
120
106
106
102
93
92
89
80
76
76

Journal

43
43
41
28
23
20
17
17
15
14
13
13
13
12
12
11
11
11
11
11

NCATS Publications

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.


Kocan M, Sarwar M, Ang SY, Xiao J, Marugan J, Hossain MA, Wang C, Hutchinson DS, Samuel CS, Agoulnik AI, Bathgate RAD, Summers RJ


Sci Rep , (7), 2968, 2017.

Article Pubmed
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Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.


Lionakis MS, Dunleavy K, Roschewski M, Widemann BC, Butman JA, Schmitz R, Yang Y, Cole DE, Melani C, Higham CS, Desai JV, Ceribelli M, Chen L, Thomas C, Little RF, Gea-Banacloche J, Bhaumik S, Stetler-Stevenson M, Pittaluga S, Jaffe ES, Heiss J, Lucas N, Steinberg SM, Staudt LM, Wilson WH


Cancer Cell , (31), 833-843.e5, 2017.

Article Pubmed
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Why are most phospholipidosis inducers also hERG blockers?


Slavov S, Stoyanova-Slavova I, Li S, Zhao J, Huang R, Xia M, Beger R


Arch. Toxicol. , 2017.

Article Pubmed
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Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.


Hsieh JH, Huang R, Lin JA, Sedykh A, Zhao J, Tice RR, Paules RS, Xia M, Auerbach SS


PLoS ONE , (12), e0177902, 2017.

Article Pubmed

Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca(2+) Efflux Channel in the Tubulovesicle.


Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer-Alegre M, Samuelson LC, Merchant JL, Xu H


Dev. Cell , (41), 262-273.e6, 2017.

Article Pubmed
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Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Using a Quantitative High-throughput Screening Platform.


Lynch C, Sakamuru S, Huang R, Stavreva DA, Varticovski L, Hager GL, Judson RS, Houck KA, Kleinstreuer NC, Casey W, Paules RS, Simeonov A, Xia M


Toxicology , 2017.

Article Pubmed
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Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.


Chen I, Mathews-Greiner L, Li D, Abisoye-Ogunniyan A, Ray S, Bian Y, Shukla V, Zhang X, Guha R, Thomas C, Gryder B, Zacharia A, Beane JD, Ravichandran S, Ferrer-Alegre M, Rudloff U


J Transl Med , (15), 92, 2017.

Article Pubmed
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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.


Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song YK, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal M, Ferrer-Alegre M, Shern JF, Zhao K, Thomas C, Khan J


Cancer Discov , 2017.

Article Pubmed

The importance of international collaboration for rare diseases research-a European perspective.


Julkowska D, Austin C, Cutillo C, Gancberg D, Hager C, Halftermeyer J, Jonker AH, Lau LPL, Norstedt I, Rath A, Schuster R, Simelyte E, van Weely S


Gene Ther. , 2017.

Article Pubmed