Program

84
22
4
3
1
1

Journal Year Published

3
17
12
19
13
8
7
8
2
1

Author

90
183
175
135
134
127
119
118
115
108
87
81
74
57
52
50
44
43
42
34

Category

57
31
27
7
4
2
1
1
1

Keyword

37
20
15
12
12
10
10
8
7
7
7
7
6
6
5
5
5
5
5
5

Journal

8
7
6
6
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1

NCATS Publications

Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors.


Singh A, Venkannagari S, Oh KH, Zhang Y, Liu L, Rohde JM, Nimmagadda S, Sudini K, Brimacombe K, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, Woo J, A Mensah G, Wang Z, Ferrer-Alegre M, Gabrielson E, Li Z, Rastinejad F, Shen M, Boxer MB, Biswal S


ACS Chem. Biol. , 2016.

Article Pubmed

Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.


Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer-Alegre M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN


J Biomol Screen , 2016.

Article Pubmed

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.


Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer-Alegre M, Xu H


Nat Commun , (7), 12109, 2016.

Article Pubmed

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Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.


Mukhopadhyay R, Roy S, Venkatadri R, Su YP, Ye W, Barnaeva E, Mathews Griner L, Southall N, Hu X, Wang A, Xu X, Dulcey AE, Marugan J, Ferrer-Alegre M, Arav-Boger R


PLoS Pathog. , (12), e1005717, 2016.

Article Pubmed

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USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.


Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer-Alegre M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, Virshup DM, Chou MM, Major MB


Proc. Natl. Acad. Sci. U.S.A. , (113), E2945-54, 2016.

Article Pubmed

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Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens.


Guha R, Mathews Griner LA, Keller JM, Zhang X, Fitzgerald D, Antignani A, Pastan I, Thomas C, Ferrer-Alegre M


J Biomol Screen , 2016.

Article Pubmed

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Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin's lymphoma.


Ju W, Zhang M, Wilson K, Petrus MN, Bamford RN, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (113), 1624-9, 2016.

Article Pubmed

Sample image from publication page