Program

131
30
10
7
7
3
2
2
1

Journal Year Published

5
9
9
7
7
12
13
17
17
12
33
21
8
3
3

Author

177
185
145
136
127
123
118
117
108
97
88
81
77
58
54
50
46
46
42
37

Category

78
66
29
29
23
12
8
8
6
4
1

Keyword

99
49
36
35
32
24
23
20
17
16
14
14
13
12
12
11
11
10
10
10

Journal

12
10
9
8
8
7
7
5
5
5
4
4
4
3
3
3
3
3
2
2

NCATS Publications

Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.


Yu D, Swaroop M, Wang M, Baxa U, Yang R, Yan Y, Coksaygan T, DeTolla L, Marugan J, Austin C, McKew JC, Gong DW, Zheng W


J Biomol Screen , (19), 1164-73, 2014.

Article Pubmed

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Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.


Blackford JA, Brimacombe K, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin C, Simons SS


Mol. Endocrinol. , (28), 1194-206, 2014.

Article Pubmed

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Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.


Hoskins JW, Ofori LO, Chen C, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan J, Zheng W, Austin C, Disney MD, Miller BL, Thornton CA


Nucleic Acids Res. , (42), 6591-602, 2014.

Article Pubmed

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Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.


Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin C, Maddocks K, Byrd J, Melnick A, Huang P, Wiestner A, Bhalla KN


Cancer Res. , (74), 2520-32, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease.


Ottinger E, Kao ML, Carrillo-Carrasco N, Yanjanin N, Shankar RK, Janssen M, Brewster M, Scott I, Xu X, Cradock J, Terse P, Dehdashti SJ, Marugan J, Zheng W, Portilla Weingarten L, Hubbs A, Pavan WJ, Heiss J, Vite CH, Walkley SU, Ory DS, Silber SA, Porter FD, Austin C, McKew JC


Curr Top Med Chem , (14), 330-9, 2014.

Pubmed

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A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology.


Trucco MM, Awad O, Wilky BA, Goldstein SD, Huang R, Walker RL, Shah P, Katuri V, Gul N, Zhu YJ, McCarthy EF, Paz-Priel I, Meltzer PS, Austin C, Xia M, Loeb DM


PLoS ONE , (8), e79950, 2013.

Article Pubmed

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High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.


Ketley A, Chen C, Li X, Arya S, Robinson TE, Granados-Riveron J, Udosen I, Morris GE, Holt I, Furling D, Chaouch S, Haworth B, Southall N, Shinn P, Zheng W, Austin C, Hayes CJ, Brook JD


Hum. Mol. Genet. , (23), 1551-62, 2014.

Article Pubmed

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