Program

164
16
7
5
3
3
2

Journal Year Published

5
23
16
20
13
26
17
13
8
16
8
10
4
2

Author

183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

79
74
72
29
15
12
6
1
1

Keyword

88
41
35
30
29
24
23
20
15
14
14
13
13
13
10
10
9
9
8
8

Journal

24
18
11
6
5
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2

NCATS Publications

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).


Rai Bantukallu G, Brimacombe K, Mott BT, Urban DJ, Hu X, Yang SM, Lee TD, Cheff D, Kouznetsova J, Benavides GA, Pohida K, Kuenstner EJ, Luci D, Lukacs CM, Davies DR, Dranow DM, Zhu H, Sulikowski G, Moore WJ, Stott GM, Flint AJ, Hall M, Darley-Usmar VM, Neckers LM, Dang CV, Waterson AG, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , (60), 9184-9204, 2017.

Article Pubmed

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Literature Search and Review.


Simeonov A, Auld D


Assay Drug Dev Technol , (15), 307-313, .

Article Pubmed

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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.


Urban DJ, Martinez N, Davis MI, Brimacombe K, Cheff D, Lee TD, Henderson M, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall M


Sci Rep , (7), 12758, 2017.

Article Pubmed

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Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold.


Teske KA, Rai Bantukallu G, Nandhikonda P, Sidhu PS, Feleke B, Simeonov A, Yasgar A, Jadhav A, Maloney DJ, Arnold LA


ACS Comb Sci , (19), 646-656, 2017.

Article Pubmed

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First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.


Adili R, Tourdot BE, Mast K, Yeung J, Freedman JC, Green A, Luci D, Jadhav A, Simeonov A, Maloney DJ, Holman TR, Holinstat M


Arterioscler. Thromb. Vasc. Biol. , (37), 1828-1839, 2017.

Article Pubmed

Drug discovery and development for rare genetic disorders.


Sun W, Zheng W, Simeonov A


Am. J. Med. Genet. A , (173), 2307-2322, 2017.

Article Pubmed

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