Program

164
16
7
5
3
3
2

Journal Year Published

16
7
23
16
20
13
26
17
13
8
16
8
10
4
2

Author

201
181
149
139
133
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

79
74
72
29
15
12
6
1
1

Keyword

88
41
35
30
29
24
23
20
15
14
14
13
13
13
10
10
9
9
8
8

Journal

26
18
11
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3

NCATS Publications

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.


Xia M, Huang R, Shi Q, Boyd WA, Zhao J, Sun N, Rice JR, Dunlap PE, Hackstadt AJ, Bridge MF, Smith MV, Dai S, Zheng W, Chu P, Gerhold D, Witt KL, DeVito M, Freedman JH, Austin C, Houck KA, Thomas RS, Paules RS, Tice RR, Simeonov A


Environ. Health Perspect. , (126), 077010, 2018.

Article Pubmed

The Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.


Coussens NP, et al.


Clin Transl Sci , 2018.

Article Pubmed

Sample image from publication page

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.


Yang S, et al.


Cell Discov , (4), 31, 2018.

Article Pubmed

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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry.


Silvestri I, Lyu H, Fata F, Boumis G, Miele AE, Ardini M, Ippoliti R, Bellelli A, Jadhav A, Lea WA, Simeonov A, Cheng Q, Arnér ESJ, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F


ACS Chem. Biol. , 2018.

Article Pubmed

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Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.


Yang SM, Martinez N, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang A, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ


J. Med. Chem. , 2018.

Article Pubmed

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Donated chemical probes for open science.


Müller S, et al.


Elife , (7), 2018.

Article Pubmed

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Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.


Horton JR, Liu X, Wu L, Zhang K, Shanks J, Zhang X, Rai Bantukallu G, Mott BT, Jansen DJ, Kales S, Henderson M, Pohida K, Fang Y, Hu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Yan Q, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page