Program

116
16
6
4
3

Journal Year Published

9
10
12
5
13
10
12
12
12
7
5
15
10
1

Author

133
201
181
149
139
133
125
123
108
105
95
82
78
63
62
54
50
46
43
43

Category

56
45
28
20
13
6
5
4
3
1

Keyword

63
35
27
25
22
17
17
17
14
11
10
10
9
9
9
9
8
7
7
7

Journal

13
9
8
7
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2

NCATS Publications

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

Sample image from publication page

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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Advancing precision medicine with personalized drug screening.


Gorshkov K, Chen C, Marshall RE, Mihatov N, Choi Y, Nguyen T, Southall N, Chen KG, Park JK, Zheng W


Drug Discov. Today , 2018.

Article Pubmed

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Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.


Luderman KD, Conroy JL, Free RB, Southall N, Ferrer-Alegre M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aubé J, Lane JR, Frankowski KJ, Sibley DR


Mol. Pharmacol. , (94), 1197-1209, 2018.

Article Pubmed

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Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.


Frankowski KJ, et al.


Sci Transl Med , (10), 2018.

Article Pubmed

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Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance.


Zhou W, et al.


Oncogene , 2018.

Article Pubmed

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Unexplored therapeutic opportunities in the human genome.


Oprea TI, et al.


Nat Rev Drug Discov , 2018.

Article Pubmed

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