Program

56
11
4
2
1
1
1
1

Journal Year Published

1
6
1
7
5
6
8
7
6
5
5

Author

57
183
175
135
134
127
119
118
115
108
90
87
81
74
52
50
44
43
42
34

Category

22
18
15
14
7
5
3
1
1

Keyword

32
15
15
13
11
10
10
9
8
8
7
7
7
6
6
6
6
6
5
5

Journal

9
6
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.


Brimacombe K, Walsh MJ, Liu L, Vásquez-Valdivieso MG, Morgan HP, McNae I, Fothergill-Gilmore LA, Michels PA, Auld DS, Simeonov A, Walkinshaw MD, Shen M, Boxer MB


ACS Med Chem Lett , (5), 12-7, 2014.

Article Pubmed

Sample image from publication page

Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.


Blackford JA, Brimacombe K, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin C, Simons SS


Mol. Endocrinol. , (28), 1194-206, 2014.

Article Pubmed

Sample image from publication page

Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.


Davis MI, Gross S, Shen M, Straley KS, Pragani R, Lea WA, Popovici-Muller J, DeLaBarre B, Artin E, Thorne N, Auld DS, Li Z, Dang L, Boxer MB, Simeonov A


J. Biol. Chem. , (289), 13717-25, 2014.

Article Pubmed

Sample image from publication page

Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.


Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin C, Maddocks K, Byrd J, Melnick A, Huang P, Wiestner A, Bhalla KN


Cancer Res. , (74), 2520-32, 2014.

Article Pubmed

Sample image from publication page

A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.


Jiang J, McCoy JG, Shen M, LeClair C, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G, Choi WS, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas C


Bioorg. Med. Chem. Lett. , (24), 1148-53, 2014.

Article Pubmed

Sample image from publication page

Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors.


Thomas AG, Rojas C, Tanega C, Shen M, Simeonov A, Boxer MB, Auld DS, Ferraris DV, Tsukamoto T, Slusher BS


Biochem. Biophys. Res. Commun. , (438), 243-8, 2013.

Article Pubmed

Sample image from publication page

Identification of potent Yes1 kinase inhibitors using a library screening approach.


Patel PR, Sun H, Li SQ, Shen M, Khan J, Thomas C, Davis MI


Bioorg. Med. Chem. Lett. , (23), 4398-403, 2013.

Article Pubmed

Sample image from publication page

Physicochemical characterization of a thermostable alcohol dehydrogenase from Pyrobaculum aerophilum.


Vitale A, Thorne N, Lovell S, Battaile KP, Hu X, Shen M, D'Auria S, Auld DS


PLoS ONE , (8), e63828, 2013.

Article Pubmed

Sample image from publication page