Program

68
19
3
3
1
1

Journal Year Published

1
12
19
13
8
7
8
2
1

Author

71
29
28
23
21
20
17
11
10
9
8
8
8
7
7
6
6
5
5
5

Category

41
27
24
6
4
2
1
1
1

Keyword

35
18
14
11
11
10
9
8
7
7
7
6
6
6
5
5
5
5
5
5

Journal

8
6
6
5
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1

NCATS Publications

Cancer network activity associated with therapeutic response and synergism.


Serra-Musach J, Mateo F, Capdevila-Busquets E, de Garibay GR, Zhang X, Guha R, Thomas C, Grueso J, Villanueva A, Jaeger S, Heyn H, Vizoso M, Pérez H, Cordero A, Gonzalez-Suarez E, Esteller M, Moreno-Bueno G, Tjärnberg A, Lázaro C, Serra V, Arribas J, Benson M, Gustafsson M, Ferrer-Alegre M, Aloy P, Pujana MÀ


Genome Med , (8), 88, 2016.

Article Pubmed

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Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors.


Singh A, Venkannagari S, Oh KH, Zhang Y, Liu L, Rohde J, Nimmagadda S, Sudini K, Brimacombe K, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, Woo J, A Mensah G, Wang Z, Ferrer-Alegre M, Gabrielson E, Li Z, Rastinejad F, Shen M, Boxer MB, Biswal S


ACS Chem. Biol. , 2016.

Article Pubmed

Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.


Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer-Alegre M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN


J Biomol Screen , 2016.

Article Pubmed

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.


Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer-Alegre M, Xu H


Nat Commun , (7), 12109, 2016.

Article Pubmed

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Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.


Mukhopadhyay R, Roy S, Venkatadri R, Su YP, Ye W, Barnaeva E, Mathews Griner L, Southall N, Hu X, Wang A, Xu X, Dulcey AE, Marugan J, Ferrer-Alegre M, Arav-Boger R


PLoS Pathog. , (12), e1005717, 2016.

Article Pubmed

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USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.


Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer-Alegre M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, Virshup DM, Chou MM, Major MB


Proc. Natl. Acad. Sci. U.S.A. , (113), E2945-54, 2016.

Article Pubmed

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Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens.


Guha R, Mathews Griner LA, Keller JM, Zhang X, Fitzgerald D, Antignani A, Pastan I, Thomas C, Ferrer-Alegre M


J Biomol Screen , 2016.

Article Pubmed

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