Program

73
20
3
3
1
1

Journal Year Published

7
12
19
13
8
7
8
2
1

Author

77
31
31
25
22
20
18
12
11
10
8
8
8
7
7
7
6
6
6
5

Category

46
29
26
6
4
2
1
1
1

Keyword

36
19
15
12
11
10
10
8
7
7
7
6
6
6
5
5
5
5
5
5

Journal

8
6
6
5
5
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1

NCATS Publications

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.


Abera MB, Xiao J, Nofziger J, Titus S, Southall N, Zheng W, Moritz KE, Ferrer-Alegre M, Cherry JJ, Androphy EJ, Wang A, Xu X, Austin C, Fischbeck KH, Marugan J, Burnett BG


JCI Insight , (1), e88427, 2016.

Article Pubmed

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A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm.


Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer-Alegre M, Chaperot L, Plumas J, Jaffe ES, Thomas C, Reizis B, Staudt LM


Cancer Cell , (30), 764-778, 2016.

Article Pubmed

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Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition.


Estrada LD, Chamorro D, Yañez MJ, Gonzalez M, Leal N, von Bernhardi R, Dulcey AE, Marugan J, Ferrer-Alegre M, Soto C, Zanlungo S, Inestrosa NC, Alvarez AR


J. Alzheimers Dis. , (54), 1193-1205, 2016.

Article Pubmed

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Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.


Antignani A, Mathews Griner L, Guha R, Simon N, Pasetto M, Keller J, Huang M, Angelus E, Pastan I, Ferrer-Alegre M, FitzGerald DJ, Thomas C


PLoS ONE , (11), e0161415, 2016.

Article Pubmed

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Cancer network activity associated with therapeutic response and synergism.


Serra-Musach J, Mateo F, Capdevila-Busquets E, de Garibay GR, Zhang X, Guha R, Thomas C, Grueso J, Villanueva A, Jaeger S, Heyn H, Vizoso M, Pérez H, Cordero A, Gonzalez-Suarez E, Esteller M, Moreno-Bueno G, Tjärnberg A, Lázaro C, Serra V, Arribas J, Benson M, Gustafsson M, Ferrer-Alegre M, Aloy P, Pujana MÀ


Genome Med , (8), 88, 2016.

Article Pubmed

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Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors.


Singh A, Venkannagari S, Oh KH, Zhang Y, Liu L, Rohde J, Nimmagadda S, Sudini K, Brimacombe K, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, Woo J, A Mensah G, Wang Z, Ferrer-Alegre M, Gabrielson E, Li Z, Rastinejad F, Shen M, Boxer MB, Biswal S


ACS Chem. Biol. , 2016.

Article Pubmed

Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.


Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer-Alegre M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN


J Biomol Screen , 2016.

Article Pubmed

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.


Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, Hu X, Gao Q, Yang M, Lawas M, Delling M, Marugan J, Ferrer-Alegre M, Xu H


Nat Commun , (7), 12109, 2016.

Article Pubmed

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