Program

769
533
98
85
83
35
26
15
15
11
10
10
9
4
2

Journal Year Published

28
88
169
317
325
375
117
61
47
47
34
17
8
4
4
3
2
2
2
2

Author

165
164
120
117
114
110
105
105
104
77
72
71
61
52
50
41
39
37
33
31

Category

314
306
283
95
85
67
21
18
15
14
3
2

Keyword

1185
579
526
359
331
294
206
180
158
143
121
113
108
105
96
94
90
80
79
76

Journal

46
45
41
28
25
21
18
17
15
14
14
13
13
13
13
13
12
12
11
11

NCATS Publications

Better living through chemistry: Addressing emerging antibiotic resistance.


Coussens N, Molinaro AL, Culbertson KJ, Peryea T, Zahoranszky-Kohalmi G, Hall M, Daines DA


Exp. Biol. Med. (Maywood) , 1535370218755659, 2018.

Article Pubmed

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Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.


Rolt A, Le D, Hu Z, Wang A, Shah P, Singleton M, Hughes E, Dulcey AE, He S, Imamura M, Uchida T, Chayama K, Xu X, Marugan J, Liang TJ


J. Infect. Dis. , 2018.

Article Pubmed

Chemical Control of a CRISPR-Cas9 Acetyltransferase.


Shrimp JH, Grose C, Widmeyer SRT, Thorpe AL, Jadhav A, Meier JL


ACS Chem. Biol. , (13), 455-460, 2018.

Article Pubmed

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Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease.


Li Z, Sakamuru S, Huang R, Brecher M, Koetzner CA, Zhang J, Chen H, Qin CF, Zhang QY, Zhou J, Kramer LD, Xia M, Li H


Antiviral Res. , 2017.

Article Pubmed

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Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development.


Wagner JA, Dahlem AM, Hudson LD, Terry SF, Altman RB, Gilliland CT, DeFeo C, Austin C


Clin Transl Sci , 2017.

Article Pubmed

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A dynamic map for learning, communicating, navigating and improving therapeutic development.


Wagner J, Dahlem AM, Hudson LD, Terry SF, Altman RB, Gilliland CT, DeFeo C, Austin C


Nat Rev Drug Discov , 2017.

Article Pubmed

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Omics-Based Platform for Studying Chemical Toxicity Using Stem Cells.


Han Y, Zhao J, Huang R, Xia M, Wang D


J. Proteome Res. , (17), 579-589, 2018.

Article Pubmed

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Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.


Pei F, Li H, Henderson M, Titus SA, Jadhav A, Simeonov A, Cobanoglu MC, Mousavi SH, Shun T, McDermott L, Iyer P, Fioravanti M, Carlisle D, Friedlander RM, Bahar I, Taylor DL, Lezon TR, Stern AM, Schurdak ME


Sci Rep , (7), 17803, 2017.

Article Pubmed

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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.


Al-Ramahi I, Panapakkam Giridharan SS, Chen Y, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer-Alegre M, Southall N, Weisman LS, Botas J, Marugan JJ


Elife , (6), 2017.

Article Pubmed

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