Program

33
3
1

Journal Year Published

1
4
3
4
1
7
3
1
1
3
4
1
2

Author

35
185
177
145
136
127
123
118
117
108
97
88
81
77
58
54
50
46
46
42
37

Category

20
14
10
5
2
1
1
1

Keyword

14
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
2

Journal

5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.


Deschamps JD, Ogunsola AF, Jameson JB, Yasgar A, Flitter BA, Freedman CJ, Melvin JA, Nguyen JV, Maloney DJ, Jadhav A, Simeonov A, Bomberger JM, Holman TR


Biochemistry , (55), 3329-40, 2016.

Article Pubmed

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.


Pacold ME, et al.


Nat. Chem. Biol. , (12), 452-8, 2016.

Article Pubmed

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Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.


Rai Bantukallu G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, Holman TR


J. Med. Chem. , (57), 4035-48, 2014.

Article Pubmed

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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.


Luci D, Jameson JB, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, Jadhav A, Simeonov A, Holman TR, Maloney DJ


J. Med. Chem. , (57), 495-506, 2014.

Article Pubmed

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A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding.


McCallum MM, Pawlak AJ, Shadrick WR, Simeonov A, Jadhav A, Yasgar A, Maloney DJ, Arnold LA


Anal Bioanal Chem , (406), 1867-75, 2014.

Article Pubmed

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