Program

92
90
5
3
2
1

Journal Year Published

16
11
20
10
8
9
10
12
12
10
12
4

Author

134
183
175
135
127
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

75
47
31
25
6
5
2
2
2
1
1

Keyword

58
41
30
19
18
16
15
15
14
13
13
12
12
11
11
10
10
10
9
9

Journal

14
13
11
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2

NCATS Publications

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.


Zanos P, Moaddel R, Morris P, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas C, Zarate CA, Gould TD


Pharmacol. Rev. , (70), 621-660, 2018.

Article Pubmed

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Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.


Dyall J, Nelson EA, DeWald LE, Guha R, Hart BJ, Zhou H, Postnikova E, Logue J, Vargas WM, Gross R, Michelotti J, Deiuliis N, Bennett RS, Crozier I, Holbrook MR, Morris P, Klumpp-Thomas C, McKnight C, Mierzwa T, Shinn P, Glass PJ, Johansen LM, Jahrling PB, Hensley LE, Olinger GG, Thomas C, White JM


J. Infect. Dis. , 2018.

Article Pubmed

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A multiprotein supercomplex controlling oncogenic signalling in lymphoma.


Phelan JD, et al.


Nature , 2018.

Article Pubmed

Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells.


Ferrer-Alegre M, Gosline SJC, Stathis M, Zhang X, Guo X, Guha R, Ryman DA, Wallace MR, Kasch-Semenza L, Hao H, Ingersoll R, Mohr D, Thomas C, Verma S, Guinney J, Blakeley JO


Sci Data , (5), 180106, 2018.

Article Pubmed

Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma.


McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Wei Y, Davani D, Guidos CJ, Khan J, Gladdy RA


Oncogene , 2018.

Article Pubmed

Characterization of clinically used oral antiseptics as quadruplex-binding ligands.


Calabrese DR, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas C, Mock BA, Schneekloth JS


Nucleic Acids Res. , 2018.

Article Pubmed

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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.


Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas C, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T


Nat. Med. , (23), 1362-1368, 2017.

Article Pubmed

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Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.


Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris P, Thomas C, Possemato R, Vander Heiden MG, Papagiannakopoulos T


Elife , (6), 2017.

Article Pubmed

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Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.


Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau D, Morris P, Zhao J, Thomas C, Monje M


Nature , (549), 533-537, 2017.

Article Pubmed

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Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma.


Heske CM, Davis MI, Baumgart JT, Wilson K, Gormally MV, Chen L, Zhang X, Ceribelli M, Duveau D, Guha R, Ferrer-Alegre M, Arnaldez FI, Ji J, Tran HL, Zhang Y, Mendoza A, Helman LJ, Thomas C


Clin. Cancer Res. , 2017.

Article Pubmed

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