Program

164
16
7
5
3
3
2

Journal Year Published

5
23
16
20
13
26
17
13
8
16
8
10
4
2

Author

183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

79
74
72
29
15
12
6
1
1

Keyword

88
41
35
30
29
24
23
20
15
14
14
13
13
13
10
10
9
9
8
8

Journal

24
18
11
6
5
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2

NCATS Publications

Inhibition of Spinal 15-LOX-1 Attenuates TLR4-Dependent, NSAID-Unresponsive Hyperalgesia in Male Rats.


Gregus AM, Buczynski MW, Dumlao DS, Norris PC, Rai Bantukallu G, Simeonov A, Maloney DJ, Jadhav A, Xu Q, Wei SC, Fitzsimmons BL, Dennis EA, Yaksh TL


Pain , 2018.

Article Pubmed

Sample image from publication page

KDM5 histone demethylases repress immune response via suppression of STING.


Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai Bantukallu G, Kales S, Henderson M, Hu X, Jadhav A, Maloney DJ, Simeonov A, Zhu S, Iwasaki A, Hall M, Cheng X, Shadel GS, Yan Q


PLoS Biol. , (16), e2006134, 2018.

Article Pubmed

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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.


Xia M, Huang R, Shi Q, Boyd WA, Zhao J, Sun N, Rice JR, Dunlap PE, Hackstadt AJ, Bridge MF, Smith MV, Dai S, Zheng W, Chu P, Gerhold D, Witt KL, DeVito M, Freedman JH, Austin C, Houck KA, Thomas RS, Paules RS, Tice RR, Simeonov A


Environ. Health Perspect. , (126), 077010, 2018.

Article Pubmed

The Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.


Coussens NP, et al.


Clin Transl Sci , 2018.

Article Pubmed

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Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.




Cell Discov , (4), 31, 2018.

Article Pubmed

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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry.


Silvestri I, Lyu H, Fata F, Boumis G, Miele AE, Ardini M, Ippoliti R, Bellelli A, Jadhav A, Lea WA, Simeonov A, Cheng Q, Arnér ESJ, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F


ACS Chem. Biol. , 2018.

Article Pubmed

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Donated chemical probes for open science.


Müller S, et al.


Elife , (7), 2018.

Article Pubmed

Sample image from publication page