Program

32
11
7
7
1

Journal Year Published

6
3
7
4
5
2
3
3
3
2
3
1
1

Author

43
183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
42
34

Category

21
21
17
4
4
4
3
1
1

Keyword

18
9
9
8
7
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3

Journal

3
3
3
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2
2
2
1
1
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1
1
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1
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1

NCATS Publications

Synergistic drug combination effectively blocks Ebola virus infection.


Sun W, He S, Martínez-Romero C, Kouznetsova J, Tawa G, Xu M, Shinn P, Fisher EG, Long Y, Motabar O, Yang S, Sanderson P, Williamson PR, García-Sastre A, Qiu X, Zheng W


Antiviral Res. , (137), 165-172, 2017.

Article Pubmed

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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.


Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall M, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A


J. Biol. Chem. , 2016.

Article Pubmed

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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.


Xu M, Lee E, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael S, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H


Nat. Med. , (22), 1101-1107, 2016.

Article Pubmed

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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.


Wang M, et al.


Nat. Biotechnol. , (34), 828-37, 2016.

Article Pubmed

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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.


Mott BT, Eastman R, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer-Alegre M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas C


Sci Rep , (5), 13891, 2015.

Article Pubmed

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Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.


Zhang M, Mathews Griner LA, Ju W, Duveau D, Guha R, Petrus MN, Wen B, Maeda M, Shinn P, Ferrer-Alegre M, Conlon KD, Bamford RN, O'Shea JJ, Thomas C, Waldmann TA


Proc. Natl. Acad. Sci. U.S.A. , (112), 12480-5, 2015.

Article Pubmed

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.


Lee JA, Shinn P, Jaken S, Oliver S, Willard FS, Heidler S, Peery RB, Oler J, Chu S, Southall N, Dexheimer TS, Smallwood J, Huang R, Guha R, Jadhav A, Cox K, Austin C, Simeonov A, Sittampalam S, Husain S, Franklin N, Wild DJ, Yang JJ, Sutherland JJ, Thomas C


PLoS ONE , (10), e0130796, 2015.

Article Pubmed

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Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs.


Kouznetsova J, Sun W, Martínez-Romero C, Tawa G, Shinn P, Chen C, Schimmer A, Sanderson P, McKew JC, Zheng W, García-Sastre A


Emerg Microbes Infect , (3), e84, 2014.

Article Pubmed

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