Program

42
5
1
1
1

Journal Year Published

7
2
5
3
7
4
6
1
3
3
1

Author

42
183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
43
34

Category

26
12
11
10
2
1
1

Keyword

22
14
9
8
7
6
6
5
5
4
4
4
3
3
3
3
3
3
3
3

Journal

10
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.


Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales S, Mott BT, Rai Bantukallu G, Jansen DJ, Henderson M, Urban DJ, Hall M, Simeonov A, Maloney DJ, Johns MA, Fu H, Jadhav A, Vertino PM, Yan Q, Cheng X


Cell Chem Biol , (23), 769-81, 2016.

Article Pubmed

Sample image from publication page

A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies.


Zhang Y, Fox JT, Park YU, Elliott G, Rai Bantukallu G, Cai M, Sakamuru S, Huang R, Xia M, Lee K, Jeon MH, Mathew BP, Park HD, Edelmann W, Park CY, Hong SY, Maloney D, Myung K


Cancer Res. , 2016.

Article Pubmed

Sample image from publication page

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.


Pacold ME, et al.


Nat. Chem. Biol. , (12), 452-8, 2016.

Article Pubmed

Sample image from publication page

Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants.


Smith SJ, Pauly GT, Akram A, Melody K, Rai Bantukallu G, Maloney DJ, Ambrose Z, Thomas C, Schneider JT, Hughes SH


Retrovirology , (13), 11, 2016.

Article Pubmed

Sample image from publication page

KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.


Duan L, Rai Bantukallu G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, Hsieh JT, Liu ZP


Chem. Biol. , (22), 1185-96, 2015.

Article Pubmed

Sample image from publication page

Discovery of a novel general anesthetic chemotype using high-throughput screening.


McKinstry-Wu AR, Bu W, Rai Bantukallu G, Lea WA, Weiser BP, Liang DF, Simeonov A, Jadhav A, Maloney DJ, Eckenhoff RG


Anesthesiology , (122), 325-33, 2015.

Article Pubmed

Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.


Taylor-Fishwick DA, Weaver J, Glenn L, Kuhn N, Rai Bantukallu G, Jadhav A, Simeonov A, Dudda A, Schmoll D, Holman TR, Maloney DJ, Nadler JL


Diabetologia , (58), 549-57, 2015.

Article Pubmed

Sample image from publication page

Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition.


Gormally MV, Dexheimer TS, Marsico G, Sanders DA, Lowe C, Matak-Vinković D, Michael S, Jadhav A, Rai Bantukallu G, Maloney DJ, Simeonov A, Balasubramanian S


Nat Commun , (5), 5165, 2014.

Article Pubmed

Sample image from publication page

Biochemical assays for the discovery of TDP1 inhibitors.


Marchand C, Huang SY, Dexheimer TS, Lea WA, Mott BT, Chergui A, Naumova A, Stephen AG, Rosenthal AS, Rai Bantukallu G, Murai J, Gao R, Maloney DJ, Jadhav A, Jorgensen WL, Simeonov A, Pommier Y


Mol. Cancer Ther. , (13), 2116-26, 2014.

Article Pubmed

Sample image from publication page

Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.


Rai Bantukallu G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, Holman TR


J. Med. Chem. , (57), 4035-48, 2014.

Article Pubmed

Sample image from publication page