Program

14
13
1
1

Journal Year Published

1
3
3
2
2
4
4
1
3

Author

23
183
175
135
134
127
119
118
115
108
90
87
81
74
57
52
50
44
43
42
34

Category

12
12
7
1
1
1
1

Keyword

17
12
11
7
6
6
6
5
5
5
4
4
4
4
4
4
3
3
3
3

Journal

4
3
3
2
1
1
1
1
1
1
1
1
1
1
1

NCATS Publications

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.


Anastasiou D, et al.


Nat. Chem. Biol. , (8), 839-47, 2012.

Article Pubmed

Sample image from publication page

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.


Anastasiou D, Poulogiannis G, Asara JM, Boxer MB, Jiang J, Shen M, Bellinger G, Sasaki AT, Locasale JW, Auld DS, Thomas C, Vander Heiden MG, Cantley LC


Science , (334), 1278-83, 2011.

Article Pubmed

Sample image from publication page

Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.


Chung S, Himmel DM, Jiang J, Wojtak K, Bauman JD, Rausch JW, Wilson JA, Beutler JA, Thomas C, Arnold E, Le Grice SF


J. Med. Chem. , (54), 4462-73, 2011.

Article Pubmed

Sample image from publication page

Chiral kinase inhibitors.


Jiang J, Shen M, Thomas C, Boxer MB


Curr Top Med Chem , (11), 800-9, 2011.

Pubmed

Sample image from publication page

CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP.


Ju W, Zhang M, Jiang J, Thomas C, Oh U, Bryant BR, Chen J, Sato N, Tagaya Y, Morris JC, Janik JE, Jacobson S, Waldmann TA


Blood , (117), 1938-46, 2011.

Article Pubmed

Sample image from publication page

Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion.


Feng J, Petersen CD, Coy DH, Jiang J, Thomas C, Pollak MR, Wank SA


Proc. Natl. Acad. Sci. U.S.A. , (107), 17791-6, 2010.

Article Pubmed

Sample image from publication page

Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Jiang J, Boxer MB, Vander Heiden MG, Shen M, Skoumbourdis AP, Southall N, Veith H, Leister W, Austin C, Park HW, Inglese J, Cantley LC, Auld DS, Thomas C


Bioorg. Med. Chem. Lett. , (20), 3387-93, 2010.

Article Pubmed

Sample image from publication page

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.


Davis RE, et al.


Nature , (463), 88-92, 2010.

Article Pubmed

Sample image from publication page

Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.


Boxer MB, Jiang J, Vander Heiden MG, Shen M, Skoumbourdis AP, Southall N, Veith H, Leister W, Austin C, Park HW, Inglese J, Cantley LC, Auld DS, Thomas C


J. Med. Chem. , (53), 1048-55, 2010.

Article Pubmed

Sample image from publication page