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NCATS Publications

Glucocerebrosidase as a therapeutic target for Parkinson's disease.


Chen Y, Sam R, Sharma P, Chen L, Do J, Sidransky E


Expert Opin. Ther. Targets , (24), 287-294, 2020.

Article Pubmed

Sample image from publication page

Chemically Defined Neural Conversion of Human Pluripotent Stem Cells.


Chen Y, Tristan C, Mallanna SK, Ormanoglu P, Titus S, Simeonov A, Singec I


Methods Mol. Biol. , (1919), 59-72, 2019.

Article Pubmed

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Detection of nanocarrier potentiation on drug induced phospholipidosis in cultured cells and primary hepatocyte spheroids by high content imaging and analysis.


Zhang X, Yang L, Liu Y, Song Z, Zhao J, Chen D, Yu H, Li R, Wang Y, Yang K, Chen Y, Xia M, Zhang LW


Toxicol. Appl. Pharmacol. , (348), 54-66, 2018.

Article Pubmed

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Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers.


Chen Y, Gershlick DC, Park SY, Bonifacino JS


J. Cell Biol. , (216), 4141-4151, 2017.

Article Pubmed

BORC coordinates encounter and fusion of lysosomes with autophagosomes.


Jia R, Guardia CM, Pu J, Chen Y, Bonifacino JS


Autophagy , (13), 1648-1663, 2017.

Article Pubmed

TSSC1 is novel component of the endosomal retrieval machinery.


Gershlick DC, Schindler C, Chen Y, Bonifacino JS


Mol. Biol. Cell , (27), 2867-78, 2016.

Article Pubmed

High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors.


He S, Jain P, Lin B, Ferrer-Alegre M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho CH, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, Marugan J, Liang TJ, Frankowski KJ


ACS Comb Sci , (17), 641-52, 2015.

Article Pubmed

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EARP is a multisubunit tethering complex involved in endocytic recycling.


Schindler C, Chen Y, Pu J, Guo X, Bonifacino JS


Nat. Cell Biol. , (17), 639-50, 2015.

Article Pubmed