Program

769
580
106
103
99
36
26
22
16
11
10
10
9
4
3

Journal Year Published

21
106
98
177
327
330
384
121
64
50
50
36
18
9
4
3
4
3
2
2

Author

182
174
134
134
125
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

375
362
314
112
85
71
21
20
19
19
3
2

Keyword

1221
594
540
383
337
299
210
195
160
145
123
121
110
107
97
97
91
83
81
81

Journal

49
49
43
28
27
24
21
18
16
16
16
15
15
15
14
14
14
14
14
13

NCATS Publications

Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.


Köhler S, et al.


Nucleic Acids Res. , (47), D1018-D1027, 2019.

Article Pubmed

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.


Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales S, Lal-Nag M, Rai Bantukallu G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K


Cancer Cell , (34), 939-953.e9, 2018.

Article Pubmed

Sample image from publication page

High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.


Jansson KH, Tucker JB, Stahl LE, Simmons JK, Fuller C, Beshiri ML, Agarwal S, Fang L, Hynes PG, Alilin AN, Lake R, Abbey YC, Cawley J, Tice CM, Yin J, McKnight C, Klumpp-Thomas C, Zhang X, Guha R, Hoover S, Simpson RM, Nguyen HM, Corey E, Thomas C, Proia DA, Kelly K


Sci Rep , (8), 17239, 2018.

Article Pubmed

Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein BRD4.


Villar-Prados A, Wu SY, Court KA, Ma S, LaFargue C, Chowdhury MA, Engelhardt MI, Ivan C, Ram PT, Wang Y, Baggerly K, Rodriguez-Aguayo C, Lopez-Berestein G, Yang SM, Maloney DJ, Yoshioka M, Strovel JW, Roszik J, Sood AK


Mol. Cancer Ther. , 2018.

Article Pubmed

Children and Adults With Rare Diseases Need Innovative Medical Devices.


Peiris V, Xu K, Agler HL, Chen EA, Gopal-Srivastava R, Lappin BM, Lewis DY, Rao GR


J Med Device , (12), 0347011-347018, 2018.

Article Pubmed

A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma.


Guenther LM, Dharia NV, Ross L, Conway A, Robichaud AL, Catlett JL, Wechsler CS, Frank ES, Goodale A, Church AJ, Tseng YY, Guha R, McKnight C, Janeway KA, Boehm JS, Mora J, Davis MI, Alexe G, Piccioni F, Stegmaier K


Clin. Cancer Res. , 2018.

Article Pubmed

Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.


Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai Bantukallu G, Mott BT, Jansen DJ, Kales S, Henderson M, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page

DrugCentral 2018: an update.


Ursu O, Holmes J, Bologa CG, Yang JJ, Mathias SL, Stathias V, Nguyen T, Schürer S, Oprea T


Nucleic Acids Res. , (47), D963-D970, 2019.

Article Pubmed

Sample image from publication page