Program

113
16
6
3
3

Journal Year Published

2
12
5
13
10
12
12
12
7
5
15
10
1

Author

116
182
174
134
134
125
118
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

55
45
28
19
12
6
5
4
3
1

Keyword

63
35
27
25
22
17
17
17
14
11
10
10
9
9
9
9
8
7
7
7

Journal

12
9
6
6
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2

NCATS Publications

A randomized, proof-of-concept clinical trial on repurposing chlorcyclizine for the treatment of chronic hepatitis C.


Koh C, Dubey P, Han MAT, Walter PJ, Garraffo HM, Surana P, Southall N, Borochov N, Uprichard SL, Cotler SJ, Etzion O, Heller T, Dahari H, Liang TJ


Antiviral Res. , (163), 149-155, 2019.

Article Pubmed

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A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha.


Sengupta N, Jović M, Barnaeva E, Kim D, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer-Alegre M, Marugan J, Balla T


J. Lipid Res. , 2019.

Article Pubmed

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DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.


Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer-Alegre M, Slusher BS


Sci Rep , (8), 17715, 2018.

Article Pubmed

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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.


Vilimas T, Wang A, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer-Alegre M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U


Cancer Chemother. Pharmacol. , 2018.

Article Pubmed

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Advancing precision medicine with personalized drug screening.


Gorshkov K, Chen C, Marshall RE, Mihatov N, Choi Y, Nguyen T, Southall N, Chen KG, Park JK, Zheng W


Drug Discov. Today , 2018.

Article Pubmed

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Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.


Luderman KD, Conroy JL, Free RB, Southall N, Ferrer-Alegre M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aubé J, Lane JR, Frankowski KJ, Sibley DR


Mol. Pharmacol. , (94), 1197-1209, 2018.

Article Pubmed

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