Program

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Journal Year Published

4
23
16
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26
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2

Author

182
174
134
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125
118
116
114
108
88
86
81
73
56
51
50
43
43
42
34

Category

79
74
72
29
14
12
6
1
1

Keyword

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41
35
30
29
24
23
20
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Journal

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NCATS Publications

Thymine DNA glycosylase as a novel target for melanoma.


Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, Testa JR, Davidson G, Davidson I, Larue L, Sobol RW, Yen TJ, Bellacosa A


Oncogene , 2019.

Article Pubmed

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.


Kearney SE, et al.


ACS Cent Sci , (4), 1727-1741, 2018.

Article Pubmed

Sample image from publication page

A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN).


Sommers JA, Kulikowicz T, Croteau DL, Dexheimer T, Dorjsuren D, Jadhav A, Maloney DJ, Simeonov A, Bohr VA, Brosh RM


PLoS ONE , (14), e0210525, 2019.

Article Pubmed

KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations.


Liu X, Zhang SM, McGeary MK, Krykbaeva I, Lai L, Jansen DJ, Kales S, Simeonov A, Hall M, Kelly DP, Bosenberg MW, Yan Q


Mol. Cancer Ther. , 2018.

Article Pubmed

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.


Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales S, Lal-Nag M, Rai Bantukallu G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K


Cancer Cell , (34), 939-953.e9, 2018.

Article Pubmed

Sample image from publication page

Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.


Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai Bantukallu G, Mott BT, Jansen DJ, Kales S, Henderson M, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page

Inhibition of Spinal 15-LOX-1 Attenuates TLR4-Dependent, NSAID-Unresponsive Hyperalgesia in Male Rats.


Gregus AM, Buczynski MW, Dumlao DS, Norris PC, Rai Bantukallu G, Simeonov A, Maloney DJ, Jadhav A, Xu Q, Wei SC, Fitzsimmons BL, Dennis EA, Yaksh TL


Pain , 2018.

Article Pubmed

Sample image from publication page