Program

130
10
5
3
3
2
2

Journal Year Published

4
20
13
26
17
13
8
16
8
10
4
2

Author

141
85
54
34
28
25
24
19
16
15
13
13
13
12
11
11
10
10
10
9

Category

67
52
46
28
10
7
6
1
1

Keyword

86
40
34
30
28
23
22
19
15
14
13
13
13
13
10
10
9
9
8
8

Journal

20
17
8
5
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2

NCATS Publications

Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Using a Quantitative High-throughput Screening Platform.


Lynch C, Sakamuru S, Huang R, Stavreva DA, Varticovski L, Hager GL, Judson RS, Houck KA, Kleinstreuer NC, Casey W, Paules RS, Simeonov A, Xia M


Toxicology , 2017.

Article Pubmed
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A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation.


Lessing D, Dial TO, Wei C, Payer B, Carrette LL, Kesner B, Szanto A, Jadhav A, Maloney DJ, Simeonov A, Theriault J, Hasaka T, Bedalov A, Bartolomei MS, Lee JT


Proc. Natl. Acad. Sci. U.S.A. , (113), 14366-14371, 2016.

Article Pubmed
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Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".


Houck KA, Judson RS, Knudsen TB, Martin MT, Richard AM, Crofton KM, Simeonov A, Paules RS, Bucher JR, Thomas RS


Environ. Health Perspect. , (125), A8-A11, 2017.

Article Pubmed

Pharos: Collating protein information to shed light on the druggable genome.


Nguyen T, Mathias S, Bologa C, Brunak S, Fernandez N, Gaulton A, Hersey A, Holmes J, Jensen LJ, Karlsson A, Liu G, Ma'ayan A, Mandava G, Mani S, Mehta S, Overington J, Patel J, Rouillard AD, Schürer S, Sheils T, Simeonov A, Sklar LA, Southall N, Ursu O, Vidovic D, Waller A, Yang J, Jadhav A, Oprea TI, Guha R


Nucleic Acids Res. , (45), D995-D1002, 2017.

Article Pubmed
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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.


Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall M, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A


J. Biol. Chem. , 2016.

Article Pubmed
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Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.


Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael S, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H


Nat. Med. , (22), 1101-1107, 2016.

Article Pubmed
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Good Cell Culture Practice for stem cells and stem-cell-derived models.


Pamies D, Bal-Price A, Simeonov A, Tagle D, Allen D, Gerhold D, Yin D, Pistollato F, Inutsuka T, Sullivan K, Stacey G, Salem H, Leist M, Daneshian M, Vemuri MC, McFarland R, Coecke S, Fitzpatrick SC, Lakshmipathy U, Mack A, Wang WB, Daiju Y, Sekino Y, Kanda Y, Smirnova L, Hartung T


ALTEX , 2016.

Article Pubmed
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