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NCATS Publications

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.


Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris P, Thomas C, Possemato R, Vander Heiden MG, Papagiannakopoulos T


Elife , (6), 2017.

Article Pubmed
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Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.


Venkatesh HS, Tam LT, Woo PJ, Lennon J, Nagaraja S, Gillespie SM, Ni J, Duveau D, Morris P, Zhao J, Thomas C, Monje M


Nature , (549), 533-537, 2017.

Article Pubmed
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Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites.


Morris P, Moaddel R, Zanos P, Moore CE, Gould T, Zarate CA, Thomas C


Org. Lett. , (19), 4572-4575, 2017.

Article Pubmed
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The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.


Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris P, Guha R, Klumpp-Thomas C, McKnight C, Chen Y, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG, White JM


PLoS Negl Trop Dis , (11), e0005540, 2017.

Article Pubmed
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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.


Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas C, Zarate CA, Gould TD


Nature , (533), 481-6, 2016.

Article Pubmed
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Impact of obesity on the survival of patients with early-stage squamous cell carcinoma of the oral tongue.


Iyengar NM, Kochhar A, Morris P, Morris LG, Zhou XK, Ghossein RA, Pino A, Fury MG, Pfister DG, Patel SG, Boyle JO, Hudis CA, Dannenberg AJ


Cancer , (120), 983-91, 2014.

Article Pubmed