Program

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2

Journal Year Published

2
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1

Author

6
183
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144
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127
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118
115
108
94
87
81
77
57
52
50
45
44
42
34

Category

3
3
2
2
1

Keyword

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2
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Journal

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1

NCATS Publications

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.


Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau D, Jiang J, Michael S, Mierzwa T, Huang W, Walsh MJ, Mott BT, Patel P, Leister W, Maloney DJ, LeClair C, Rai Bantukallu G, Jadhav A, Peyser BD, Austin C, Martin SE, Simeonov A, Ferrer-Alegre M, Staudt LM, Thomas C


Proc. Natl. Acad. Sci. U.S.A. , (111), 2349-54, 2014.

Article Pubmed

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A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.


Jiang J, McCoy JG, Shen M, LeClair C, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G, Choi WS, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas C


Bioorg. Med. Chem. Lett. , (24), 1148-53, 2014.

Article Pubmed

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Separation of Betti Reaction Product Enantiomers: Absolute Configuration and Inhibition of Botulinum Neurotoxin A.


Cardellina JH, Vieira RC, Eccard V, Skerry J, Montgomery V, Campbell Y, Roxas-Duncan V, Leister W, LeClair C, Maloney DJ, Padula D, Pescitelli G, Khavrutskii I, Hu X, Wallqvist A, Smith LA


ACS Med Chem Lett , (2), 396-401, 2011.

Article Pubmed

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Phosphodiesterase 4 inhibitors enhance sexual pleasure-seeking activity in rodents.


Yuan P, Tragon T, Xia M, LeClair C, Skoumbourdis AP, Zheng W, Thomas C, Huang R, Austin C, Chen G, Guitart X


Pharmacol. Biochem. Behav. , (98), 349-55, 2011.

Article Pubmed

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Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.


Skoumbourdis AP, LeClair C, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin C, Michnick SW, Xia M, Thomas C


Bioorg. Med. Chem. Lett. , (19), 3686-92, 2009.

Article Pubmed

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