Program

48
24
9
6
1

Journal Year Published

3
8
11
8
7
6
10
5
2
1

Author

61
25
19
10
9
9
8
8
8
6
6
6
6
5
5
5
5
4
4
4

Category

27
26
23
17
5
3
2
1

Keyword

25
13
12
10
6
6
6
5
5
5
4
4
4
4
4
4
3
3
3
3

Journal

7
6
5
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1

NCATS Publications

Characterization of clinically used oral antiseptics as quadruplex-binding ligands.


Calabrese DR, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas C, Mock BA, Schneekloth JS


Nucleic Acids Res. , 2018.

Article Pubmed

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Unexplored therapeutic opportunities in the human genome.


Oprea TI, et al.


Nat Rev Drug Discov , 2018.

Article Pubmed

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Drug target ontology to classify and integrate drug discovery data.


Lin Y, Mehta S, Küçük-McGinty H, Turner JP, Vidovic D, Forlin M, Koleti A, Nguyen T, Jensen LJ, Guha R, Mathias SL, Ursu O, Stathias V, Duan J, Nabizadeh N, Chung C, Mader C, Visser U, Yang JJ, Bologa CG, Oprea TI, Schürer SC


J Biomed Semantics , (8), 50, 2017.

Article Pubmed

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The Chemistry Development Kit (CDK) v2.0: atom typing, depiction, molecular formulas, and substructure searching.


Willighagen EL, Mayfield JW, Alvarsson J, Berg A, Carlsson L, Jeliazkova N, Kuhn S, Pluskal T, Rojas-Chertó M, Spjuth O, Torrance G, Evelo CT, Guha R, Steinbeck C


J Cheminform , (9), 33, 2017.

Article Pubmed

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Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma.


Heske CM, Davis MI, Baumgart JT, Wilson K, Gormally MV, Chen L, Zhang X, Ceribelli M, Duveau D, Guha R, Ferrer-Alegre M, Arnaldez FI, Ji J, Tran HL, Zhang Y, Mendoza A, Helman LJ, Thomas C


Clin. Cancer Res. , 2017.

Article Pubmed

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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.


Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song YK, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal M, Ferrer-Alegre M, Shern JF, Zhao K, Thomas C, Khan J


Cancer Discov , 2017.

Article Pubmed

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.


Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris P, Guha R, Klumpp-Thomas C, McKnight C, Chen Y, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG, White JM


PLoS Negl Trop Dis , (11), e0005540, 2017.

Article Pubmed

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