Program

46
22
9
7
1

Journal Year Published

5
12
9
7
6
10
6
2
1

Author

58
25
20
10
9
9
8
8
7
6
6
6
6
5
5
5
4
4
4
4

Category

27
26
19
18
5
3
1
1

Keyword

26
13
13
11
7
6
6
6
5
5
5
4
4
4
4
4
4
4
3
3

Journal

7
6
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1

NCATS Publications

Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.


Chen I, Mathews-Greiner L, Li D, Abisoye-Ogunniyan A, Ray S, Bian Y, Shukla V, Zhang X, Guha R, Thomas C, Gryder B, Zacharia A, Beane JD, Ravichandran S, Ferrer-Alegre M, Rudloff U


J Transl Med , (15), 92, 2017.

Article Pubmed
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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.


Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song YK, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal M, Ferrer-Alegre M, Shern JF, Zhao K, Thomas C, Khan J


Cancer Discov , 2017.

Article Pubmed

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.


Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris P, Guha R, Klumpp-Thomas C, McKnight C, Chen Y, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG, White JM


PLoS Negl Trop Dis , (11), e0005540, 2017.

Article Pubmed
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Pharos: Collating protein information to shed light on the druggable genome.


Nguyen T, Mathias S, Bologa C, Brunak S, Fernandez N, Gaulton A, Hersey A, Holmes J, Jensen LJ, Karlsson A, Liu G, Ma'ayan A, Mandava G, Mani S, Mehta S, Overington J, Patel J, Rouillard AD, Schürer S, Sheils T, Simeonov A, Sklar LA, Southall N, Ursu O, Vidovic D, Waller A, Yang J, Jadhav A, Oprea TI, Guha R


Nucleic Acids Res. , (45), D995-D1002, 2017.

Article Pubmed
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Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.


Cong Y, et al.


PLoS ONE , (11), e0166318, 2016.

Article Pubmed

A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm.


Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer-Alegre M, Chaperot L, Plumas J, Jaffe ES, Thomas C, Reizis B, Staudt LM


Cancer Cell , (30), 764-778, 2016.

Article Pubmed
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Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.


Antignani A, Mathews Griner L, Guha R, Simon N, Pasetto M, Keller J, Huang M, Angelus E, Pastan I, Ferrer-Alegre M, FitzGerald DJ, Thomas C


PLoS ONE , (11), e0161415, 2016.

Article Pubmed
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