Program

69
19
3
3
1
1

Journal Year Published

2
12
19
13
8
7
8
2
1

Author

72
30
29
24
20
19
17
11
10
9
8
8
8
7
7
7
6
5
5
5

Category

42
28
25
6
4
2
1
1
1

Keyword

36
19
15
12
11
10
10
8
7
7
7
6
6
6
5
5
5
5
5
5

Journal

8
6
6
5
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1

NCATS Publications

Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma.


McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Wei Y, Davani D, Guidos CJ, Khan J, Gladdy RA


Oncogene , 2018.

Article Pubmed

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.


Al-Ramahi I, Panapakkam Giridharan SS, Chen Y, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer-Alegre M, Southall N, Weisman LS, Botas J, Marugan JJ


Elife , (6), 2017.

Article Pubmed

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Matrix Screen Identifies Synergistic Combination of PARP Inhibitors and Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors in Ewing Sarcoma.


Heske CM, Davis MI, Baumgart JT, Wilson K, Gormally MV, Chen L, Zhang X, Ceribelli M, Duveau D, Guha R, Ferrer-Alegre M, Arnaldez FI, Ji J, Tran HL, Zhang Y, Mendoza A, Helman LJ, Thomas C


Clin. Cancer Res. , 2017.

Article Pubmed

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Development of an Aryloxazole Class of Hepatitis C Virus Inhibitors Targeting the Entry Stage of the Viral Replication Cycle.


He S, Li K, Lin B, Hu Z, Xiao J, Hu X, Wang A, Xu X, Ferrer-Alegre M, Southall N, Zheng W, Aubé J, Schoenen FJ, Marugan J, Liang TJ, Frankowski KJ


J. Med. Chem. , (60), 6364-6383, 2017.

Article Pubmed

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Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca(2+) Efflux Channel in the Tubulovesicle.


Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer-Alegre M, Samuelson LC, Merchant JL, Xu H


Dev. Cell , (41), 262-273.e6, 2017.

Article Pubmed

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Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.


Chen I, Mathews-Greiner L, Li D, Abisoye-Ogunniyan A, Ray S, Bian Y, Shukla V, Zhang X, Guha R, Thomas C, Gryder B, Zacharia A, Beane JD, Ravichandran S, Ferrer-Alegre M, Rudloff U


J Transl Med , (15), 92, 2017.

Article Pubmed

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PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.


Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song YK, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal M, Ferrer-Alegre M, Shern JF, Zhao K, Thomas C, Khan J


Cancer Discov , 2017.

Article Pubmed