Program

769
529
97
84
82
33
26
15
15
11
10
10
9
4
2

Journal Year Published

17
88
169
317
325
374
117
61
47
46
34
17
8
4
3
3
2
2
1
2

Author

164
162
120
114
114
110
104
103
103
75
71
71
64
52
50
40
37
37
32
31

Category

309
300
279
93
85
66
21
18
15
14
2
2

Keyword

1179
576
522
358
328
293
206
180
155
143
120
113
107
104
96
94
89
80
79
76

Journal

45
45
41
28
25
21
18
17
15
14
13
13
13
13
13
12
12
12
11
11

NCATS Publications

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.


Horton JR, Liu X, Wu L, Zhang K, Shanks J, Zhang X, Rai Bantukallu G, Mott BT, Jansen D, Kales S, Henderson M, Pohida K, Fang Y, Hu X, Jadhav A, Maloney DJ, Hall M, Simeonov A, Fu H, Vertino PM, Yan Q, Cheng X


J. Med. Chem. , 2018.

Article Pubmed

Sample image from publication page

Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma.


McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer-Alegre M, Thomas C, Wei Y, Davani D, Guidos CJ, Khan J, Gladdy RA


Oncogene , 2018.

Article Pubmed

Characterization of clinically used oral antiseptics as quadruplex-binding ligands.


Calabrese DR, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas C, Mock BA, Schneekloth JS


Nucleic Acids Res. , 2018.

Article Pubmed

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Unexplored therapeutic opportunities in the human genome.


Oprea TI, et al.


Nat Rev Drug Discov , 2018.

Article Pubmed

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A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.


Mav D, Shah RR, Howard BE, Auerbach SS, Bushel PR, Collins JB, Gerhold D, Judson RS, Karmaus AL, Maull EA, Mendrick DL, Merrick BA, Sipes NS, Svoboda D, Paules RS


PLoS ONE , (13), e0191105, 2018.

Article Pubmed

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Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.


Stafford WC, Peng X, Olofsson MH, Zhang X, Luci D, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens N, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ


Sci Transl Med , (10), 2018.

Article Pubmed

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Literature Search and Review.


Simeonov A, Wilson A, Auld D


Assay Drug Dev Technol , 2018.

Article Pubmed

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